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Barbiturates seem to enhance the metabolism of exogenous corticosteroids likely through the induction of hepatic microsomal enzymes. Sufferers stabilized on corticosteroid therapy might require dosage changes if barbiturates are included to or withdrawn from their dosage program.
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Corticosteroids: Barbiturates look to boost the metabolism of exogenous corticosteroids in all probability in the induction of hepatic microsomal enzymes. Sufferers stabilized on corticosteroid therapy could call for dosage adjustments if barbiturates are included to or withdrawn from their dosage regimen.
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DOSAGE AND ADMINISTRATION Dosages of barbiturates must be individualized with total familiarity with their unique characteristics and advised charge of administration.
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